The Dafabet Warriors and DP World Lions have secured their places in the YesPlay Pro20 Cup semifinals, while Dafabet Boland and YesPlay Cobras are firmly in the driving seat to claim the remaining two spots ahead of the final round of Super 8 matches.
Both Boland and Cobras will qualify for the last four if they win their respective final fixtures.
Boland face the Lions at home on Wednesday, while the Cobras host Garden Route Badgers at YesPlay Newlands on Tuesday evening.
The Badgers and Momentum Multiply Titans remain in contention, but their qualification hopes to depend on other results going their way.
A defeat for either side will see them eliminated, with the Badgers needing a result against Cobras and Titans facing an uphill task against Warriors in Centurion.
The Warriors and Lions have already done enough to progress, while Hollywoodbets Dolphins and World Sports Betting Eastern Storm have been eliminated.
The permutations follow a rain-affected penultimate round, which saw the Warriors and Lions emerge as the biggest beneficiaries after the Titans and Dolphins were forced to share the spoils at SuperSport Park in Centurion on Sunday.
Only three overs were possible in the match, with the Dolphins reaching 28 without loss before the game was officially abandoned due to inclement weather.
The result ended the Dolphins' hopes of reaching the semifinals, while the Titans were left needing a strong finish in their final fixture.
There was, however, a full match at WSB Willowmoore Park in Benoni, where defending champions Warriors defeated Eastern Storm by 20 runs to move to the top of the Super 8 standings with one round remaining.
The visitors were sent in to bat, but Eastern Storm struggled to make inroads as Warriors' opening pair of Jordan Hermann and Sibonelo Makhanya put together a century stand.
Hermann was dismissed for 33, while Makhanya top-scored with an impressive 74.
Tristan Stubbs then provided further impetus with an unbeaten 48, supported by JP King's 25, as the Warriors posted a formidable 206-4 in their 20 overs.
In reply, Ronan Hermann led Eastern Storm's chase with a well-compiled 56, receiving support from Kabelo Sekhukhune and Brayden Hicks.
Christopher Britz offered the strongest resistance, scoring 63 before being dismissed with just one ball remaining.
However, his efforts could not prevent Eastern Storm from falling short, as they finished on 186-9 and at the bottom of the Super 8 standings.
The final round gets underway on Tuesday evening when Cobras host Badgers in Cape Town, before Boland welcome Lions in Paarl on Wednesday.
The Titans will then have one final opportunity to keep their semifinal hopes alive when they take on the Warriors in Centurion.
With two semifinal places still to be decided, the final round promises a compelling finish to the Super 8 stage, with every result carrying significant consequences.